Kunyumba

 

KolajeniNdi gawo lalikulu la extracellular matrix (ECM), lomwe limapezeka makamaka pakhungu la munthu, mafupa, cartilage, mano, tendon, ligaments, ndi mitsempha yamagazi. Ndi puloteni yofunika kwambiri ya kapangidwe ka minofu yolumikizirana.

Collagen ndi gawo lalikulu la dermis ya khungu la munthu. Pamodzi ndi elastin yochepa, imapanga netiweki yokhazikika ya ulusi wa collagen, zomwe zimapangitsa khungu kukhala lolimba komanso lolimba ndipo zimathandiza kuti epidermal layer inyamule chinyezi.

Komabe, zinthu monga ukalamba, kuwala kwa dzuwa, kusuta fodya, ndi moyo wosakhala wabwino zimapangitsa kuti collagen ichepe. Pamene collagen itayika kwambiri, zizindikiro za ukalamba monga kutayika kwa kulimba kwa khungu, kutsika, makwinya, utoto, kuuma, khungu louma, ndi khungu lofewa pang'onopang'ono zimawonekera.

Ndiye, pamene collagen ikuchepa, kodi mankhwala opangidwa ndi collagen pakamwa angathandize kuchepetsa ukalamba?

Kodi ma peptide a collagen oral amatha kuyamwa ndi thupi?

Zinthu zomwe zimapezeka nthawi zambiri mu collagen zimatanthauza ma peptide a collagen, osati collagen.

KolajeniMa peptide ndi osakaniza ma peptide otsika kulemera kwa mamolekyulu okhala ndi kulemera kwapakati kwa ma Da 2000 mpaka 10,000 komwe kumapangidwa ndi hydrolyzed kuchokera ku collagen (300,000 Da). Poyerekeza ndi collagen yolemera kwambiri, ma peptide a collagen ali ndi kulemera kochepa kwa mamolekyulu ndipo amagayidwa mosavuta ndikuyamwa.

Kuphatikiza apo, ma dipeptide ndi ma tripeptide omwe ali mu ma collagen peptides amatengedwa mwachindunji ndikuyamwa ngati ma peptides ndi oligopeptide transporter protein (PepT1) yomwe ili m'maselo a epithelial a m'matumbo ang'onoang'ono. Amatha kulunjika kumalo enaake m'thupi kuti agwire ntchito komanso kuti agwire bwino ntchito.

Watanabe-Kamiyama M. ndi ena adameza ma peptide a collagen okhala ndi zilembo 14C m'ziwalo zosiyanasiyana za mbewa ndipo adawona kufalikira kwama peptide a kolajeni.

Kafukufukuyu adawonetsa kuti ma peptide a collagen opangidwa mkamwa adagawidwa ku ziwalo zazikulu m'thupi lonse pambuyo poti kugaya ndi kuyamwa, ndipo adayikidwa makamaka m'maselo okhala ndi collagen yambiri, makamaka pakhungu, pakapita nthawi inayake.

Kodi Ma Collagen Peptides Opangidwa ndi Oral Angathandize Kuthetsa Matenda a Khungu?

M'zaka zaposachedwapa, maphunziro ambiri atsimikizira kuti ma peptide a collagen opangidwa m'kamwa amachedwetsa kukalamba kwa khungu ndikubwezeretsa khungu.

Ofufuza anasankha anthu 64 odzipereka azaka zapakati pa 40 ndi 60 kuti atenge 1000 mg ya ma collagen peptides otsika kwambiri patsiku kwa milungu 12 ndipo adapeza kuti patatha milungu 6 atamwa, madzi a khungu anali bwino kwambiri, ndipo patatha milungu 12, makwinya ndi kusinthasintha kwa khungu kunakula, zomwe zikusonyeza zotsatira zotsutsana ndi ukalamba. Zotsatira zake zinasonyeza kusintha kwakukulu pakusunga chinyezi pakhungu patatha milungu 6 atamwa komanso zotsatira zotsutsana ndi ukalamba patatha milungu 12.