Ndi chifukwa chabwino,gelatinndi chimodzi mwazinthu zomwe zimagwiritsidwa ntchito kwambiri pazamankhwala ndi zamankhwala.Imalekerera pafupifupi padziko lonse lapansi, imakhala yopindulitsa kwambiri komanso imamveka bwino, imasungunuka ndi kutentha kwa thupi, ndipo imatha kutentha.Gelatin ndi chinthu chosinthika kwambiri chomwe chili ndi zabwino zosiyanasiyana pazamankhwala monga makapisozi ndi mapiritsi, pakati pa ena.
Zipolopolo zolimba komanso zofewa za makapisozi nthawi zambiri zimapangidwa ndi gelatin, zomwe zimateteza bwino zomwe zili mkati kuti zisawonongeke ndi mpweya, kukula kwa tizilombo toyambitsa matenda, kuwala, mpweya, kuipitsidwa, ndi kukoma ndi fungo.
Makapisozi Olimba
75 peresenti ya msika wa gelatin capsule amapangidwa ndi makapisozi olimba.1 Amatchulidwanso kuti makapisozi amitundu iwiri ndipo amapangidwa ndi zipolopolo ziwiri zozungulira zomwe zimamata ndi kapu yomwe imakwanira bwino pathupi.Kwa anthu, amatha kupangidwa kukula kwake kuyambira 00 mpaka 5, komanso amatha kukhala owoneka bwino kapena amitundu.Ndizothekanso kusindikiza.
Ufa, ma granules, pellets, ndi mapiritsi ang'onoang'ono amagwiritsidwa ntchito pafupipafupi ngati zodzaza makapisozi olimba.Pogwiritsa ntchito njira zomwe zimapangidwira kusindikiza ndi kuyika makapisozi potsatira malamulo otetezedwa ndi mankhwala, amathanso kudzazidwa ndi zakumwa ndi phala.
Makapisozi Ofewa
Makapisozi ofewa, kumbali ina, amapindula nawomankhwala gelatinKutha kusungunuka m'madzi otentha ndikukhazikika pakuzizira.Iwo ali ndi chidutswa chimodzi, hermetically losindikizidwa flexible chipolopolo.Amatha kupanga zipolopolo zamitundu yosiyanasiyana ndi mitundu pogwiritsa ntchito madzi kapena semi-solid filler.
Ngakhale kuti amangowerengera pafupifupi 25% ya msika wa kapisozi wa gelatin, makapisozi ofewa ali ndi maubwino osiyanasiyana pamitundu yambiri yanthawi zonse yapakamwa.Zimaphatikizapo kumeza kwachulukidwe, kutetezedwa kwa ma API, komanso kusungunuka mwachangu kwamadzi am'mimba am'mimba.Kuphatikiza apo, poyerekeza ndi mitundu yokhazikika ya mlingo, kuyamwa kwa zinthu zosasungunuka bwino zomwe zili m'makapisozi ofewa kumatha kuonjezedwa.
Mapiritsi
Gelatin itha kugwiritsidwa ntchito ngati zokutira kapena zomangira pamapiritsi, zomwe zimapereka njira yotsika mtengo ku makapisozi.Palibe mwayi wolumikizana ndi mapiritsi, omwe amaperekanso mwayi wosankha kugawa kwa mlingo.
Mapiritsi, kumbali ina, angagwiritsidwe ntchito ndi zowonjezera zowonjezera ndi APIs, ndipo kusungunuka kumakhala pang'onopang'ono, kupanga kumakhala kovuta kwambiri, ndipo pali chitetezo chochepa cha zigawo zogwira ntchito kuchokera ku mpweya ndi kuwala.Komanso, kumeza kumakhala kovuta kwambiri.
Pa granulation, gelatin imatha kukhala ngati chomangira kuti igwiritsire ufa monga wowuma, zotumphukira za cellulose, ndi chingamu cha mthethe.Kupaka kwa gelatin kungathandizenso kuthana ndi zofooka za mapiritsi.Zimaphatikizapo kupititsa patsogolo kumeza, kuchepetsa kukoma ndi kununkhira, komanso kuthandizira kuteteza ma API ku mpweya ndi kuwala, pakati pa zinthu zina.
Zida Zachipatala
Gelatin ili ndi zabwino zingapo zomwe zimapangitsa kuti ikhale yabwino pamagwiritsidwe osiyanasiyana azaumoyo.Ndi pafupifupi konsekonse kulolera, ali kwambiri cytocompatibility ndi zochepa immunogenicity.Imayeretsedwanso kwambiri popanda chiwopsezo choyipitsidwa ndipo, kuphatikiza pazigawo zowongolera zakuthupi, imapereka kupanga kwapamwamba kwambiri.
Kugwiritsiridwa ntchito kwake kumaphatikizapo masiponji a hemostatic, omwe samangosiya kutuluka kwa magazi, komanso amakhala ndi bioabsorbable ndikufulumizitsa machiritso mwa kulimbikitsa kusamuka kwa maselo atsopano a minofu.Pakadali pano, zigamba za ostomy zimagwiritsa ntchito gelatin ngati zomatira pakhungu.
Chonde khalani omasuka kulumikizana nafe Gelken, katswiriwopanga gelatin ku China, kuti mudziwe zambiri komanso mafotokozedwe.
Nthawi yotumiza: Mar-09-2023
