KUGWIRITSA NTCHITO KWA GELATIN MU ZINTHU ZONSE ZA BIOMEDICAL
Gelatin, chinthu chachilengedwe cha biopolymer, ndi chowonjezera cha chakudya chokonzedwa ndi hydrolysis yochepa ya mafupa a nyama, zikopa, tendons, tendons ndi mamba.Palibe chomwe chingafanane ndi mtundu uwu wa zinthu zamoyo mu gelatin, chifukwa cha biodegradability, biocompatibility wabwino, gel osakaniza ndi mtengo wotsika.Chifukwa chake, gelatin yakhala ikugwiritsidwa ntchito kwambiri ngati chithandizo chamankhwala chachikhalidwe muzinthu zamankhwala.
MagaziSubstitutes
Kuthiridwa mwazi kumakhala kofunika nthawi zambiri, monga opaleshoni yochepa kapena kutaya magazi kwakukulu.Komabe, kuchepa kwa gwero la magazi, kusanjika kwa magazi movutikira, komanso chiwopsezo cha magazi a allogeneic zimalepheretsanso nthawi yake, kuchita bwino komanso chitetezo chamankhwala kwambiri.Njira yolowa m'malo mwa plasma imatha kuthetsa mavutowa, chifukwa chake ili ndi kuthekera kwakukulu kogwiritsa ntchito chipatala komanso malo owongolera luso.Chifukwa chake, zida za gelatin, monga succinyl gelatin ndi polygelatin peptide, zimagwiritsidwa ntchito kwambiri m'malo mwa plasma m'chipatala.Gelatin m'malo mwa plasma idzagwiritsidwa ntchito pakagwa mwadzidzidzi monga kuchepa kwa magazi ndi kugwedezeka.Kulowa kwa Colloid kumatha kukulitsa kuchuluka kwa magazi ndikuwongolera ma microcirculation.Gelatin m'malo magazi ali ndi ubwino zambiri, monga degradability, lalikulu lolowera, sanali poizoni, sanali immunogenicity ndi zina zotero.
Hzopatsa chidwiMzakuthupi
M'zaka zaposachedwapa, gulu lachipatala lapereka chidwi kwambiri pa chitukuko cha zipangizo zatsopano za hemostatic.Siponji yotsekemera ya gelatin yakopa chidwi kwambiri chifukwa ili ndi ubwino wa zotsatira zabwino za hemostatic, mtengo wotsika komanso mphamvu zowonongeka.The hemostatic limagwirira gelatin hemostatic siponji makamaka kupanga reticular dongosolo ndi kutsekereza mitsempha, kuti agglutinate kupatsidwa zinthu za m`mwazi ndi gawo fibrinogen.Izi ndizopindulitsa kwambiri pakupanga thrombosis, kuti muchepetse nthawi ya coagulation ndipo pamapeto pake kusiya magazi.Malinga ndi momwe zimagwirira ntchito, siponji ya gelatin ya hemostatic imakhala ndi ntchito yayikulu pakuponderezana kwamakina ndi kuyamwa kwamadzi.Mu njira yonse ya coagulation, mwachitsanzo, sizimathandiza kwambiri polimbikitsa mbadwo wa njira zofunika kwambiri za hemostatic monga kutsegula kwa prothrombin.Siponji yoyamwa ya gelatin yomwe imagwiritsidwa ntchito m'chipatala imakhala ndi zovuta zambiri, monga kuchuluka kwa matupi akunja, kuchepa kwamphamvu kwa hemostatic komanso kugwa kosavuta.Pakadali pano, gelatin nthawi zambiri imasinthidwa kapena kuphatikizidwa ndi zinthu zina kuti ipange zida za hemostatic zomwe zimagwira ntchito bwino.
ZinaAzovuta
Gelatin makamaka imachokera ku kolajeni m'matenda amthupi, motero ili ndi zinthu zodziwika bwino zachilengedwe, monga kuyanjana kwabwino komanso kuwonongeka kwachilengedwe, kotero yakhala ikugwiritsidwa ntchito kwambiri m'munda wa zamankhwala.Gelatin angagwiritsidwe ntchito osati pazimenezi, komanso pochiza matenda a khungu.Mwachitsanzo, gelatin ya hydrolyzed imatha kuchiza khungu lophwanyika, ichthyosis ndi dandruff.Kuphatikiza apo, gelatin imagwiritsidwanso ntchito kwambiri muzamankhwala amkati.Mu Chinese Pharmacopoeia, akufotokozedwa kuti macromolecular gelatin imakhala ndi zotsatira za kuuma konyowa ndi kutulutsa magazi, ndipo imakhala ndi zotsatira zochiritsira pazizindikiro zambiri monga kuchepa kwa magazi ndi kutaya magazi.Gelatin ya hydrolyzed imakhalanso ndi zotsatira zoonekeratu pochiza matenda a gastritis ndi zizindikiro zina.
Nthawi yotumiza: Aug-11-2021
